Histological measurement of retinal nerve fibre layer thickness

Retinal nerve fibre layer polarimetry: histological and clinical comparison.

AIMS To compare histological thickness of the retinal nerve fibre layer in the primate with retardation measurements obtained in vivo using the Mark II Nerve Fiber Analyzer (NFA, Laser Diagnostic Technologies, San Diego, USA). METHODS Scanning laser polarimetry was performed on both eyes of a healthy anaesthetised adult primate (Macaca mulatta). The retinal nerve fibre layer thickness was mea...

Retinal nerve fibre layer thickness in ARSACS: myelination or hypertrophy?

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) was first described in the French-Canadian founder population of Quebec in 1978, but genetically confirmed patients have now been reported in individuals from Europe and Japan. Ataxia, dysarthria, spasticity with extensor plantar reflexes, distal muscle wasting, sensorimotor neuropathy and horizontal gaze-evoked nystagmus consti...

Effects of artefacts on scanning laser polarimetry of retinal nerve fibre layer thickness measurement.

AIMS To investigate the effects of artefacts on scanning laser polarimetry of the retinal nerve fibre layer. METHODS Six eyes of six normal volunteers and an artificial nerve fibre layer were examined using the nerve fibre analyser II. The retinal nerve fibre layer thickness (RNFLT) was measured in each of four 90 degree quadrants, superior (S), temporal (T), inferior (I), and nasal (N), at 1...

EVects of artefacts on scanning laser polarimetry of retinal nerve fibre layer thickness measurement

Aims—To investigate the eVects of artefacts on scanning laser polarimetry of the retinal nerve fibre layer. Methods—Six eyes of six normal volunteers and an artificial nerve fibre layer were examined using the nerve fibre analyser II. The retinal nerve fibre layer thickness (RNFLT) was measured in each of four 90 degree quadrants, superior (S), temporal (T), inferior (I), and nasal (N), at 1.5 ...

POLARIMETRIC MEASUREMENT OF THE RETINAL NERVE FIBRE LAYER PhD Thesis